PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL

Catalog number BNC882969-100

Price for BNC882969-100

Size / count 1x 100 µL

About this product

This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882969-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BCEI, Breast Cancer Estrogen Inducible Protein, Gastrointestinal Trefoil Protein, Gastrointestinal trefoil protein pS2, HP1A, HPS2, pNR2, TFF1, Trefoil Factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TFF1
Gene ID: 7031
NCBI Gene ID: 162807
UniProt: P04155
Swiss Prot: P04155
Host: Rabbit
Species Reactivity: Cynomolgus, Human
Reactivity: PNR-2|pS2|TFF1
Immunogen: Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human pS2.
Target Antigen: pNR-2 | pS2 | TFF1
Clonality: Recombinant Monoclonal
Clone: TFF1/2969R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Endocrinology
Positive Control: Breast or Ovarian carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 6.5 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL?

The catalog number for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL is BNC882969-100.

What sizes are available for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL?

PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL in stock?

PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL?

PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF488A conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.