CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL

Catalog number BNC881796-100

Price for BNC881796-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM) . CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881796-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B-lymphocyte cell adhesion molecule (BL-CAM) ; B-cell receptor CD22; CD22; Lectin 2; Lyb8; Sialic acid-binding Ig-like lectin 2 (Siglec-2) ; SIGLEC2; T-cell surface antigen Leu-14
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD22
Gene ID: 933
NCBI Gene ID: 579691
UniProt: P20273
Swiss Prot: P20273
Host: Mouse
Species Reactivity: Human
Reactivity: BL-CAM|CD22
Immunogen: Recombinant fragment of human CD22 protein (around aa 52-178) (exact sequence is proprietary)
Target Antigen: BL-CAM | CD22
Clonality: Monoclonal
Clone: BLCAM/1796
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |WB (verified)
Field of Research: Immunology
Positive Control: Raji or Ramos cells (IF/FACS). Raji cell lysate (WB). Human tonsil, lymph node or spleen (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 130-140 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL?

The catalog number for CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL is BNC881796-100.

What sizes are available for CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL?

CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL in stock?

CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL?

CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.