Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL — image 1 of 2

Product details

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL

Catalog number BNC682883-500

Price for BNC682883-500

Size / count 1x 500 µL

About this product

DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC682883-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA topoisomerase I; TOP1MT; Topoisomerase I mitochondrial; Type IB Topoisomerase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TOP1MT
Gene ID: 116447
NCBI Gene ID: 528574
UniProt: Q969P6
Swiss Prot: Q969P6
Host: Rabbit
Species Reactivity: Human
Reactivity: Topoisomerase I, Mitochondrial
Immunogen: Recombinant full-length human TOP1MT protein
Target Antigen: Topoisomerase I, Mitochondrial
Clonality: Recombinant Monoclonal
Clone: TOP1MT/2883R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cell cycle
Positive Control: A431 cells. Heart, Skeletal muscle, brain or fetal liver.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL?

The catalog number for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL is BNC682883-500.

What sizes are available for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL in stock?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ab061270361e107a36/msds/bnc682883-500.pdf.

What is Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF568 conjugate, 0.1mg/mL used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.