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Product details

Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL

Catalog number BNC682960-500

Price for BNC682960-500

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Size / count 1x 500 µL

About this product

Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alphalpha-helicalcoiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. The antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC682960-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CMD1I; CSM1; CSM2; DES; Intermediate filament protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DES
Gene ID
1674
NCBI Gene ID
594952
UniProt
P17661
Swiss Prot
P17661
Host
Rabbit
Species Reactivity
Chicken, Hamster, Human, Rat
Reactivity
Desmin
Immunogen
Recombinant full-length human DES protein
Target Antigen
Desmin
Clonality
Recombinant Monoclonal
Clone
DES/2960R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
SJRH30 Cells. Uterus or Leiomyosarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL?

The catalog number for Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL is BNC682960-500.

What sizes are available for Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL in stock?

Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ae061270361e108bb5/msds/bnc682960-500.pdf.

What is Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate, 0.1mg/mL used for?

Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alphalpha-helicalcoiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for disting

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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