• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL

Catalog number BNC682026-500

Price for BNC682026-500

Sign In for Pricing

Size / count 1x 500 µL

About this product

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out) . The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. This MAb reacts with all isoforms of CD45R expressed by all hematopoietic cells, except erythrocytes, having a higher level of expression on lymphocytes than on granulocytes (Workshop IV) . Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC682026-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B220, CD45R, GP180, Leukocyte common antigen (LCA), Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C (PTPRC), Receptor-type tyrosine-protein phosphatase C, T200 glycoprotein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PTPRC
Gene ID
5788
NCBI Gene ID
654514
UniProt
P08575
Swiss Prot
P08575
Host
Rabbit
Species Reactivity
Human
Reactivity
CD45|LCA
Immunogen
Recombinant full-length human CD45 protein
Target Antigen
CD45 | LCA
Clonality
Recombinant Monoclonal
Clone
PTPRC/1783R PTPRC/1975R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Immunology, Signal transduction
Positive Control
Ramos, U-698, or GA-10 cells. Tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
180-220 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL?

The catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL is BNC682026-500.

What sizes are available for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL in stock?

CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b9061270361e10c62a/msds/bnc682026-500.pdf.

What is CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF568 conjugate, 0.1mg/mL used for?

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5,

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

You Might Also Like
CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL
CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470391-100
TGF-beta (1D11.16.8), CF740 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740977-500
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF594 conjugate, 0.1mg/mL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940679-500
ACTH (Adrenocorticotrophic Hormone) (AH26), CF740 conjugate, 0.1mg/mL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740026-500
CD3e (B-B12), CF640R conjugate, 0.1mg/mL
CD3e (B-B12), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC401052-100
FOXP3 (3G3), CF488A conjugate, 0.1mg/mL
FOXP3 (3G3), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880645-100
CD1a (O10 + C1A/711), CF647 conjugate, 0.1mg/mL
CD1a (O10 + C1A/711), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470717-500
WT1 (Wilm's Tumor 1) (WT1/857), CF405S conjugate, 0.1mg/mL
WT1 (Wilm's Tumor 1) (WT1/857), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040857-100