Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL

Catalog number BNC681600-500

Price for BNC681600-500

Size / count 1x 500 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19) . Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC681600-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: K1B; KRT1B; Keratin; type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT77; KRT76
Gene ID: 374454; 51350
NCBI Gene ID: 334989 ; 654392
UniProt: Q7Z794; Q01546
Swiss Prot: Q7Z794 ; Q01546
Host: Rabbit
Species Reactivity: Human
Reactivity: Cytokeratin, pan
Immunogen: Recombinant full-length human KRT76 and KRT77 proteins
Target Antigen: Cytokeratin, pan
Clonality: Recombinant Monoclonal
Clone: KRTH/1576R KRTL/1577R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: Skin, Adeno- or Squamous carcinomas
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40-67 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL is BNC681600-500.

What sizes are available for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL?

Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL in stock?

Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL?

Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c01d/msds/bnc681600-500.pdf.

What is Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF568 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.