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Product details

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL

Catalog number BNC681922-500

Price for BNC681922-500

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Size / count 1x 500 µL

About this product

Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC681922-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
MSA; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TPO
Gene ID
7173
NCBI Gene ID
467554
UniProt
P07202
Swiss Prot
P07202
Host
Mouse
Species Reactivity
Human
Reactivity
TPO
Immunogen
Recombinant fragment of human TPO (around aa 685-804) (Exact sequence is proprietary)
Target Antigen
TPO
Clonality
Monoclonal
Clone
TPO/1922
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Endocrinology
Positive Control
Thyroid Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL?

The catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL is BNC681922-500.

What sizes are available for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL in stock?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL?

The safety data sheet for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0295061270361e0ffd6e/msds/bnc681922-500.pdf.

What is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF568 conjugate, 0.1mg/mL used for?

Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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