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Product details

Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL

Catalog number BNC682122-500

Price for BNC682122-500

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Size / count 1x 500 µL

About this product

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC682122-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; Ubiquitin; Ubiquitin B
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
UBB
Gene ID
7314
NCBI Gene ID
356190 and 520348
UniProt
P0CG47; P0CG48; P62979; P62987 and P62988
Swiss Prot
P0CG47; P0CG48; P62979; P62987 and P62988
Host
Mouse
Species Reactivity
Human
Reactivity
Ubiquitin
Immunogen
Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
Target Antigen
Ubiquitin
Clonality
Monoclonal
Clone
UBB/2122
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Ubiquitination
Positive Control
HeLa or Jurkat cells. Alzheimer s Brain
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
9 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL?

The catalog number for Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL is BNC682122-500.

What sizes are available for Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL in stock?

Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109ce2/msds/bnc682122-500.pdf.

What is Ubiquitin (Autophagy Marker) (UBB/2122), CF568 conjugate, 0.1mg/mL used for?

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin lig

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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