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Product details

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL

Catalog number BNC682600-100

Price for BNC682600-100

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Size / count 1x 100 µL

About this product

EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC682600-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Erbb1 variant III; ERBB1 variant III; HER1 variant III; Proto-oncogene c-ErbB-1 variant III; Receptor Tyrosine Protein Kinase variant III; ErbB1 variant III
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EGFR
Gene ID
1956
NCBI Gene ID
488293
UniProt
P00533
Swiss Prot
P00533
Host
Rabbit
Species Reactivity
Human
Reactivity
EGFRvIII
Immunogen
KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)
Target Antigen
EGFRvIII
Clonality
Recombinant Monoclonal
Clone
GFR/2600R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Signal transduction
Positive Control
A431 cells. Placenta, Breast, Colon or Bladder Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~145 kDa (vIII variant)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL?

The catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL is BNC682600-100.

What sizes are available for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL in stock?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ab061270361e107a3c/msds/bnc682600-100.pdf.

What is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF568 conjugate, 0.1mg/mL used for?

EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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