Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL — image 1 of 2

Product details

Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL

Catalog number BNC682890-100

Price for BNC682890-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein (amino acid 482) of 55 kDa (in vivo 110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyzes the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic) . Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5€TM-deoxy-5-fluorouridine to 5-FU) . High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC682890-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ECGF; ECGF1; Gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; PD-ECGF; PDECGF; Platelet-derived endothelial cell growth factor; TdRPase; Thymidine phosphorylase; TP; Tymp
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TYMP
Gene ID: 1890
NCBI Gene ID: 180903
UniProt: P19971
Swiss Prot: P19971
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Reactivity: PD-ECGF|Thymidine Phosphorylase
Immunogen: Recombinant full-length human Thymidine Phosphorylase (TP / PD-ECGF) protein
Target Antigen: PD-ECGF | Thymidine Phosphorylase
Clonality: Recombinant Monoclonal
Clone: TYMP/2890R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Angiogenesis, Metabolism
Positive Control: HUVEC cells. Breast, Bladder, Lung or Kaposi tumors
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 55 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL?

The catalog number for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL is BNC682890-100.

What sizes are available for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL?

Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL in stock?

Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL?

Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b6061270361e10b7e4/msds/bnc682890-100.pdf.

What is Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF568 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.