Product details
Catalog number BNC682168-100
Price for BNC682168-100
Size / count 1x 100 µL
Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is BNC682168-100.
Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a1061270361e1040ff/msds/bnc682168-100.pdf.
Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.