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Product details

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL

Catalog number BNC682168-100

Price for BNC682168-100

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Size / count 1x 100 µL

About this product

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC682168-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
EMD; Emerin; Emery Dreifuss muscular dystrophy (EDMD) ; STA
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EMD
Gene ID
2010
NCBI Gene ID
522823
UniProt
P50402
Swiss Prot
P50402
Host
Mouse
Species Reactivity
Human
Reactivity
Emerin
Immunogen
Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)
Target Antigen
Emerin
Clonality
Monoclonal
Clone
EMD/2168
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Organelle markers
Positive Control
K-562, HeLa or Jurkat cells. Kidney or Skin
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
37 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL?

The catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is BNC682168-100.

What sizes are available for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL in stock?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a1061270361e1040ff/msds/bnc682168-100.pdf.

What is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF568 conjugate, 0.1mg/mL used for?

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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