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Product details
Catalog number BNC681778-100
Price for BNC681778-100
Size / count 1x 100 µL
Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin α and spectrinβ are present in erythrocytes, whereas spectrin α II (also designated fodrin α ) and spectrinβ I (also designated fodrinβ ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrinβ III is highly homologous to both spectrinβ I and spectrinβ II. Spectrinβ III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Spectrin beta III (SPTBN2) (SPTBN2/1778), CF568 conjugate, 0.1mg/mL is BNC681778-100.
Spectrin beta III (SPTBN2) (SPTBN2/1778), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Spectrin beta III (SPTBN2) (SPTBN2/1778), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Spectrin beta III (SPTBN2) (SPTBN2/1778), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Spectrin beta III (SPTBN2) (SPTBN2/1778), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Spectrin beta III (SPTBN2) (SPTBN2/1778), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e100122/msds/bnc681778-100.pdf.
Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.
Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.
