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Product details
Catalog number BNC681907-100
Price for BNC681907-100
Size / count 1x 100 µL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF568 conjugate, 0.1mg/mL is BNC681907-100.
STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ad061270361e108266/msds/bnc681907-100.pdf.
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.
