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Product details

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL

Catalog number BNC682035-100

Price for BNC682035-100

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Size / count 1x 100 µL

About this product

ZAP70 is a 70 kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC682035-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Selective T cell defect; SRK; STD; Syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; TZK; Zeta chain associated protein kinase 70kDa
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ZAP70
Gene ID
7535
NCBI Gene ID
234569
UniProt
P43403
Swiss Prot
P43403
Host
Mouse
Species Reactivity
Human
Reactivity
ZAP70
Immunogen
Recombinant fragment of human ZAP70 protein (around aa 247-382) (exact sequence is proprietary)
Target Antigen
ZAP70
Clonality
Monoclonal
Clone
ZAP70/2035
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Immunology
Positive Control
Jurkat cells. Tonsil or lymph node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL?

The catalog number for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL is BNC682035-100.

What sizes are available for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL in stock?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL?

The safety data sheet for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c3cb/msds/bnc682035-100.pdf.

What is ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2035), CF568 conjugate, 0.1mg/mL used for?

ZAP70 is a 70 kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP70 expression is an excellent

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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