Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL — image 1 of 2

Product details

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL

Catalog number BNC942289-500

Price for BNC942289-500

Size / count 1x 500 µL

About this product

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942289-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: IGKC
Gene ID: 3514
NCBI Gene ID: 449609
UniProt: P01601; P01834
Swiss Prot: P01601 & P01834
Host: Rabbit
Species Reactivity: Human
Reactivity: Human Kappa Light Chain
Immunogen: Recombinant full-length human Ig kappa chain (IGKC) protein
Target Antigen: Human Kappa Light Chain
Clonality: Recombinant Monoclonal
Clone: KLC2289R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Immunology, Inflammation
Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~22.5 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL?

The catalog number for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL is BNC942289-500.

What sizes are available for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL?

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL in stock?

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL?

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2289R), CF594 conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.