Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL — image 1 of 2

Product details

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL

Catalog number BNC942313-500

Price for BNC942313-500

Size / count 1x 500 µL

About this product

This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942313-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: OSRC; Osteosarcoma; p105-Rb; PP105; pp110; pRb; Prepro retinoblastoma associated protein; RB1; Retinoblastoma 1; Retinoblastoma-associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: RB1
Gene ID: 5925
NCBI Gene ID: 408528
UniProt: P06400
Swiss Prot: P06400
Host: Rabbit
Species Reactivity: Human, Mouse
Reactivity: Rb1
Immunogen: Recombinant full-length human Rb1 protein
Target Antigen: Rb1
Clonality: Recombinant Monoclonal
Clone: RB1/2313R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Tumor suppressors
Positive Control: HeLa, A431 or BT-20 cells. Breast or Colon carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 105 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL?

The catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL is BNC942313-500.

What sizes are available for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL in stock?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF594 conjugate, 0.1mg/mL used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.