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Product details
Catalog number BNC942024-500
Price for BNC942024-500
Size / count 1x 500 µL
This antibody recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Tyrosinase (Melanoma Marker) (TYR/2024R), CF594 conjugate, 0.1mg/mL is BNC942024-500.
Tyrosinase (Melanoma Marker) (TYR/2024R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Tyrosinase (Melanoma Marker) (TYR/2024R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Tyrosinase (Melanoma Marker) (TYR/2024R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Tyrosinase (Melanoma Marker) (TYR/2024R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Tyrosinase (Melanoma Marker) (TYR/2024R), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
This antibody recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that cata
Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
