BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL — image 1 of 4

Product details

BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL

Catalog number BNC942425-500

Price for BNC942425-500

Size / count 1x 500 µL

About this product

BOB-1 is a transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2, boosting the promoter activity of those complexes. It is essential for the response of B-cells to antigens, required for the formation of germinal centers, and regilates IL-6 expression. BOB-1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB-1. Conversely, only some cases of classical Hodgkin lymphoma show BOB-1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB-1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942425-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BOB-1; B-cell-specific coactivator OBF-1; OCT-binding factor 1; POU domain class 2-associating factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: POU2AF1
Gene ID: 5450
NCBI Gene ID: 654525
UniProt: Q16633
Swiss Prot: Q16633
Host: Mouse
Species Reactivity: Human
Reactivity: BOB.1
Immunogen: Recombinant fragment of human BOB1 (POU2AF1) protein (around aa 148-255) (exact sequence is proprietary)
Target Antigen: BOB.1
Clonality: Monoclonal
Clone: BOB1/2425
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Immunology
Positive Control: Raji and Ramos cells. Spleen or Tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL?

The catalog number for BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL is BNC942425-500.

What sizes are available for BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL in stock?

BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL?

The safety data sheet for BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is BOB.1 (B-Cell Marker) (BOB1/2425), CF594 conjugate, 0.1mg/mL used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.