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Product details

Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL

Catalog number BNC941940-500

Price for BNC941940-500

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Size / count 1x 500 µL

About this product

Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941940-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Chromosome 10 open reading frame 59; MAO C; MAO-C; Monoamine oxidase-C; Renalase; Renalase FAD dependent amine oxidase; RNLS
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
RNLS
Gene ID
55328
NCBI Gene ID
149849
UniProt
Q5VYX0
Swiss Prot
Q5VYX0
Host
Mouse
Species Reactivity
Human
Reactivity
Renalase
Immunogen
Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)
Target Antigen
Renalase
Clonality
Monoclonal
Clone
RNLS/1940
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Endocrinology, Metabolism
Positive Control
293T Cells. Heart or Kidney
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
38 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL?

The catalog number for Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL is BNC941940-500.

What sizes are available for Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL?

Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL in stock?

Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL?

Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Renalase (Renal Cell Marker) (RNLS/1940), CF594 conjugate, 0.1mg/mL used for?

Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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