Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL

Catalog number BNC941810-500

Price for BNC941810-500

Size / count 1x 500 µL

About this product

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous Î± andÎ2 chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Î± I and spectrinÎ2 I are present in erythrocytes, whereas spectrin Î± II (also designated fodrin Î±) and spectrinÎ2 II (also designated fodrinÎ2) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941810-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Alpha I spectrin; Elliptocytosis 2 (EL2) ; Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SPTA1
Gene ID: 6708
NCBI Gene ID: 119825
UniProt: P02549
Swiss Prot: P02549
Host: Mouse
Species Reactivity: Human
Reactivity: Spectrin Alpha 1
Immunogen: Recombinant human SPTA fragment (around aa356-475) (exact sequence is proprietary)
Target Antigen: Spectrin Alpha 1
Clonality: Monoclonal
Clone: SPTA1/1810
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cytoskeleton
Positive Control: Jurkat cells. Placenta or Tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 240 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: , BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL?

The catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL is BNC941810-500.

What sizes are available for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL in stock?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF594 conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.