TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL

Catalog number BNC941922-500

Price for BNC941922-500

Size / count 1x 500 µL

About this product

Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941922-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: MSA; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TPO
Gene ID: 7173
NCBI Gene ID: 467554
UniProt: P07202
Swiss Prot: P07202
Host: Mouse
Species Reactivity: Human
Reactivity: TPO
Immunogen: Recombinant fragment of human TPO (around aa 685-804) (Exact sequence is proprietary)
Target Antigen: TPO
Clonality: Monoclonal
Clone: TPO/1922
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Endocrinology
Positive Control: Thyroid Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL?

The catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL is BNC941922-500.

What sizes are available for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL in stock?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL?

The safety data sheet for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF594 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.