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Product details

Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL

Catalog number BNC942122-500

Price for BNC942122-500

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Size / count 1x 500 µL

About this product

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942122-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; Ubiquitin; Ubiquitin B
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
UBB
Gene ID
7314
NCBI Gene ID
356190 and 520348
UniProt
P0CG47; P0CG48; P62979; P62987 and P62988
Swiss Prot
P0CG47; P0CG48; P62979; P62987 and P62988
Host
Mouse
Species Reactivity
Human
Reactivity
Ubiquitin
Immunogen
Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
Target Antigen
Ubiquitin
Clonality
Monoclonal
Clone
UBB/2122
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Ubiquitination
Positive Control
HeLa or Jurkat cells. Alzheimer s Brain
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
9 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL?

The catalog number for Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL is BNC942122-500.

What sizes are available for Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL in stock?

Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ubiquitin (Autophagy Marker) (UBB/2122), CF594 conjugate, 0.1mg/mL used for?

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin lig

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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