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Product details

Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL

Catalog number BNC941969-100

Price for BNC941969-100

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Size / count 1x 100 µL

About this product

Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941969-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AITD3; hTG; TDH3; Tg; Tgn
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TG
Gene ID
7038
NCBI Gene ID
654591
UniProt
P01266
Swiss Prot
P01266
Host
Mouse
Species Reactivity
Human
Reactivity
Thyroglobulin
Immunogen
Human thyroid follicular cells
Target Antigen
Thyroglobulin
Clonality
Recombinant Monoclonal
Clone
R6E1
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
Thyroid
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
660 kDa (Dimeric Form)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL?

The catalog number for Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL is BNC941969-100.

What sizes are available for Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL in stock?

Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF594 conjugate, 0.1mg/mL used for?

Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticu

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

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