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Product details
Catalog number BNC942883-100
Price for BNC942883-100
Size / count 1x 100 µL
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF594 conjugate, 0.1mg/mL is BNC942883-100.
Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous antican
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
