MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL — image 1 of 2

Product details

MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL

Catalog number BNC942111-100

Price for BNC942111-100

Size / count 1x 100 µL

About this product

The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942111-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC5; HSAP; MSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MSH6
Gene ID: 2956
NCBI Gene ID: 445052
UniProt: P52701
Swiss Prot: P52701
Host: Mouse
Species Reactivity: Human
Reactivity: MSH6
Immunogen: Recombinant fragment of human MSH6 protein (around aa 374-540) (exact sequence is proprietary)
Target Antigen: MSH6
Clonality: Monoclonal
Clone: MSH6/2111
Type: Primary
Source: Animal
Origin: Animal
Field of Research: DNA repair
Positive Control: A431 or HeLa cells. Colon Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 85 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL?

The catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL is BNC942111-100.

What sizes are available for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL in stock?

MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100467/msds/bnc942111-100.pdf.

What is MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), CF594 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.