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Product details

TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL

Catalog number BNC942085-100

Price for BNC942085-100

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Size / count 1x 100 µL

About this product

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942085-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Enhancer of split groucho 1 (ESG1) ; Enhancer of split groucho-like protein 1; GRG1; TLE1; Transducin like enhancer of split 1; Transducin-like enhancer protein 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TLE1
Gene ID
7088
NCBI Gene ID
197320; 689805
UniProt
Q04724
Swiss Prot
Q04724
Host
Mouse
Species Reactivity
Human
Reactivity
TLE1
Immunogen
Recombinant fragment (aa 175-338) of human TLE1 (exact sequence is proprietary)
Target Antigen
TLE1
Clonality
Monoclonal
Clone
TLE1/2085
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
83 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL?

The catalog number for TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL is BNC942085-100.

What sizes are available for TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL?

TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL in stock?

TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL?

TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL?

The safety data sheet for TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, 0.1mg/mL used for?

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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