EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL — image 1 of 3

Product details

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL

Catalog number BNC402600-500

Price for BNC402600-500

Size / count 1x 500 µL

About this product

EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402600-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Erbb1 variant III; ERBB1 variant III; HER1 variant III; Proto-oncogene c-ErbB-1 variant III; Receptor Tyrosine Protein Kinase variant III; ErbB1 variant III
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EGFR
Gene ID: 1956
NCBI Gene ID: 488293
UniProt: P00533
Swiss Prot: P00533
Host: Rabbit
Species Reactivity: Human
Reactivity: EGFRvIII
Immunogen: KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)
Target Antigen: EGFRvIII
Clonality: Recombinant Monoclonal
Clone: GFR/2600R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Signal transduction
Positive Control: A431 cells. Placenta, Breast, Colon or Bladder Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~145 kDa (vIII variant)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL?

The catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL is BNC402600-500.

What sizes are available for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL in stock?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF640R conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.