CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL

Catalog number BNC402026-500

Price for BNC402026-500

Size / count 1x 500 µL

About this product

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out) . The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. This MAb reacts with all isoforms of CD45R expressed by all hematopoietic cells, except erythrocytes, having a higher level of expression on lymphocytes than on granulocytes (Workshop IV) . Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402026-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B220, CD45R, GP180, Leukocyte common antigen (LCA), Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C (PTPRC), Receptor-type tyrosine-protein phosphatase C, T200 glycoprotein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PTPRC
Gene ID: 5788
NCBI Gene ID: 654514
UniProt: P08575
Swiss Prot: P08575
Host: Rabbit
Species Reactivity: Human
Reactivity: CD45|LCA
Immunogen: Recombinant full-length human CD45 protein
Target Antigen: CD45 | LCA
Clonality: Recombinant Monoclonal
Clone: PTPRC/1783R PTPRC/1975R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Immunology, Signal transduction
Positive Control: Ramos, U-698, or GA-10 cells. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 180-220 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL?

The catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL is BNC402026-500.

What sizes are available for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL in stock?

CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD45 / LCA (Leucocyte Marker) (PTPRC/1783R + PTPRC/1975R), CF640R conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.