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Product details

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL

Catalog number BNC402313-500

Price for BNC402313-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402313-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
OSRC; Osteosarcoma; p105-Rb; PP105; pp110; pRb; Prepro retinoblastoma associated protein; RB1; Retinoblastoma 1; Retinoblastoma-associated protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
RB1
Gene ID
5925
NCBI Gene ID
408528
UniProt
P06400
Swiss Prot
P06400
Host
Rabbit
Species Reactivity
Human, Mouse
Reactivity
Rb1
Immunogen
Recombinant full-length human Rb1 protein
Target Antigen
Rb1
Clonality
Recombinant Monoclonal
Clone
RB1/2313R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Tumor suppressors
Positive Control
HeLa, A431 or BT-20 cells. Breast or Colon carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
105 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL?

The catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL is BNC402313-500.

What sizes are available for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL in stock?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF640R conjugate, 0.1mg/mL used for?

This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does no

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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