CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL — image 1 of 3

Product details

CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL

Catalog number BNC402507-500

Price for BNC402507-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 145 kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs) . A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402507-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD11 antigen-like family member C; Complement component 3 receptor 4 subunit; Integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide) ; Leu M5 alpha subunit; Leukocyte adhesion glycoprotein p150 95 alpha chain; Myeloid membrane antigen alpha subunit; p150/95
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ITGAX
Gene ID: 3687
NCBI Gene ID: 248472
UniProt: P20702
Swiss Prot: P20702
Host: Mouse
Species Reactivity: Human
Reactivity: CD11c
Immunogen: Recombinant fragment of human ITGAX protein (around aa 637-827) (exact sequence is proprietary)
Target Antigen: CD11c
Clonality: Monoclonal
Clone: ITGAX/2507
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Cell adhesion, Immunology
Positive Control: THP-1 cells. Tonsil or Lymph Node
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 145 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL?

The catalog number for CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL is BNC402507-500.

What sizes are available for CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL?

CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL in stock?

CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL?

CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD11c (Dendritic Cell Marker) (ITGAX/2507), CF640R conjugate, 0.1mg/mL used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.