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Product details

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL

Catalog number BNC401810-500

Price for BNC401810-500

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Size / count 1x 500 µL

About this product

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous α andÎ2 chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin α I and spectrinÎ2 I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrinÎ2 II (also designated fodrinÎ2) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401810-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Alpha I spectrin; Elliptocytosis 2 (EL2) ; Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SPTA1
Gene ID
6708
NCBI Gene ID
119825
UniProt
P02549
Swiss Prot
P02549
Host
Mouse
Species Reactivity
Human
Reactivity
Spectrin Alpha 1
Immunogen
Recombinant human SPTA fragment (around aa356-475) (exact sequence is proprietary)
Target Antigen
Spectrin Alpha 1
Clonality
Monoclonal
Clone
SPTA1/1810
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cytoskeleton
Positive Control
Jurkat cells. Placenta or Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
240 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2c, kappa
Species
, BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL?

The catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL is BNC401810-500.

What sizes are available for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL in stock?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF640R conjugate, 0.1mg/mL used for?

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizer

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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