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Product details

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL

Catalog number BNC402883-100

Price for BNC402883-100

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Size / count 1x 100 µL

About this product

DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402883-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
DNA topoisomerase I; TOP1MT; Topoisomerase I mitochondrial; Type IB Topoisomerase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TOP1MT
Gene ID
116447
NCBI Gene ID
528574
UniProt
Q969P6
Swiss Prot
Q969P6
Host
Rabbit
Species Reactivity
Human
Reactivity
Topoisomerase I, Mitochondrial
Immunogen
Recombinant full-length human TOP1MT protein
Target Antigen
Topoisomerase I, Mitochondrial
Clonality
Recombinant Monoclonal
Clone
TOP1MT/2883R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cell cycle
Positive Control
A431 cells. Heart, Skeletal muscle, brain or fetal liver.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL?

The catalog number for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL is BNC402883-100.

What sizes are available for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL in stock?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1015f2/msds/bnc402883-100.pdf.

What is Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF640R conjugate, 0.1mg/mL used for?

DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous antican

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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