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Product details

Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL

Catalog number BNC401980-100

Price for BNC401980-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401980-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
IDDM2; ILPR; IRDN; MODY10; Proinsulin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
INS
Gene ID
3630
NCBI Gene ID
272259
UniProt
P01308
Swiss Prot
P01308
Host
Rabbit
Species Reactivity
Cow, Human, Mouse, Pig, Rabbit
Reactivity
Insulin|IRDN
Immunogen
Recombinant human full-length Insulin protein (IRDN)
Target Antigen
Insulin | IRDN
Clonality
Recombinant Monoclonal
Clone
IRDN/1980R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Endocrinology
Positive Control
MIA PaCa-2 cells. Pancreas.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
6 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL?

The catalog number for Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL is BNC401980-100.

What sizes are available for Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL?

Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL in stock?

Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL?

Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Insulin / IRDN (beta-Cell & Insulinoma Marker) (IRDN/1980R), CF640R conjugate, 0.1mg/mL used for?

This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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