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Product details
Catalog number BNC402890-100
Price for BNC402890-100
Size / count 1x 100 µL
This antibody recognizes a protein (amino acid 482) of 55 kDa (in vivo 110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyzes the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic) . Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5€TM-deoxy-5-fluorouridine to 5-FU) . High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF640R conjugate, 0.1mg/mL is BNC402890-100.
Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Thymidine Phosphorylase / PD-ECGF (Angiogenesis Marker) (TYMP/2890R), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102c96/msds/bnc402890-100.pdf.
This antibody recognizes a protein (amino acid 482) of 55 kDa (in vivo 110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyzes the reversible phospholytic cle
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
