SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL — image 1 of 4

Product details

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL

Catalog number BNC402540-100

Price for BNC402540-100

Size / count 1x 100 µL

About this product

SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF-β -induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival in vitro and for primary tumor growth and metastasis in vivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402540-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: SOX; SRY (sex determining region Y) box 4; SRY box containing gene 4; SRY related HMG box gene 4; Transcription factor SOX-4
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SOX4
Gene ID: 6659
NCBI Gene ID: 643910
UniProt: Q06945
Swiss Prot: Q06945
Host: Mouse
Species Reactivity: Human
Reactivity: SOX4
Immunogen: Recombinant full-length human SOX4 protein
Target Antigen: SOX4
Clonality: Monoclonal
Clone: SOX4/2540
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Developmental biology, Transcription factors
Positive Control: Breast or Colon Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 47 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL?

The catalog number for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL is BNC402540-100.

What sizes are available for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL?

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL in stock?

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL?

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL?

The safety data sheet for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), CF640R conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.