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Product details

STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL

Catalog number BNC401907-100

Price for BNC401907-100

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Size / count 1x 100 µL

About this product

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401907-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
APRF; HIES; ADMIO; ADMIO1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
STAT3
Gene ID
6774
NCBI Gene ID
463059
UniProt
P40763
Swiss Prot
P40763
Host
Mouse
Species Reactivity
Human
Reactivity
STAT3
Immunogen
Recombinant full-length human STAT3 protein
Target Antigen
STAT3
Clonality
Monoclonal
Clone
PCRP-STAT3-2F12
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Immunology, Inflammation, Signal transduction, Transcription factors
Positive Control
A431 and Raji cells. Kidney, Brain or Heart
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
88 kDa
References & Citations
Zhong, Z., et al. 1994. Science 264: 95-98
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL?

The catalog number for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL is BNC401907-100.

What sizes are available for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL?

STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL in stock?

STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL?

STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL?

The safety data sheet for STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL used for?

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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