• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472290-500

Price for BNC472290-500

Sign In for Pricing

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP) -activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472290-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7) ; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CFTR
Gene ID
1080
NCBI Gene ID
489786, 621460, 661104
UniProt
P13569
Swiss Prot
P13569
Host
Rabbit
Species Reactivity
Human, Mouse
Reactivity
CFTR
Immunogen
Recombinant full-length human CFTR protein
Target Antigen
CFTR
Clonality
Recombinant Monoclonal
Clone
CFTR/2290R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Ion channels
Positive Control
MOLT-4 cells. Pancreas, Kidney or Placenta.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
165-170 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

The catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is BNC472290-500.

What sizes are available for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL in stock?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e100f93/msds/bnc472290-500.pdf.

What is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) prot

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

You Might Also Like
CD3e (CRIS-7), CF647 conjugate, 0.1mg/mL
CD3e (CRIS-7), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471050-100
Cytokeratin 8/18 (C-51), CF568 conjugate, 0.1mg/mL
Cytokeratin 8/18 (C-51), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680034-500
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880225-500
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680204-100
P27 / KIP1 (SX53G8), CF405S conjugate, 0.1mg/mL
P27 / KIP1 (SX53G8), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040669-500
CD71 (66IG10), CF647 conjugate, 0.1mg/mL
CD71 (66IG10), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470871-500
Cytokeratin, LMW (AE-1), CF647 conjugate, 0.1mg/mL
Cytokeratin, LMW (AE-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470253-500
CD47 (B6H12.2), CF740 conjugate, 0.1mg/mL
CD47 (B6H12.2), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740437-100