EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL — image 1 of 3

Product details

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472600-500

Price for BNC472600-500

Size / count 1x 500 µL

About this product

EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472600-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Erbb1 variant III; ERBB1 variant III; HER1 variant III; Proto-oncogene c-ErbB-1 variant III; Receptor Tyrosine Protein Kinase variant III; ErbB1 variant III
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EGFR
Gene ID: 1956
NCBI Gene ID: 488293
UniProt: P00533
Swiss Prot: P00533
Host: Rabbit
Species Reactivity: Human
Reactivity: EGFRvIII
Immunogen: KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)
Target Antigen: EGFRvIII
Clonality: Recombinant Monoclonal
Clone: GFR/2600R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Signal transduction
Positive Control: A431 cells. Placenta, Breast, Colon or Bladder Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~145 kDa (vIII variant)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL?

The catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL is BNC472600-500.

What sizes are available for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL in stock?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e1028fd/msds/bnc472600-500.pdf.

What is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.