Galectin-1 / Human Placental Lactogen (hPL) (GAL1/2499R), CF647 conjugate, 0.1mg/mL

About this product

Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC472499-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

14kDa laminin-binding protein; Beta-galactoside-binding lectin L-14-I; Gal-1; GAL1; Galaptin; Galectin-1; HLBP14; HPL; Lactose-binding lectin 1; Lect14; Lectin galactoside-binding soluble 1; LGALS1; MAPK activating protein MP12; S-Lac lectin 1

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

LGALS1

Gene ID

3956

NCBI Gene ID

445351

UniProt

P09382

Swiss Prot

P09382

Host

Rabbit

Species Reactivity

Human

Reactivity

Galectin-1|Human Placental Lactogen

Immunogen

Recombinant human Galectin-1 protein fragment (aa12-108) (exact sequence is proprietary)

Target Antigen

Galectin-1 | Human Placental Lactogen

Clonality

Recombinant Monoclonal

Clone

GAL1/2499R

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified) |WB (verified)

Field of Research

Cancer, Immunology

Positive Control

HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

14 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG

Species

Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF647