Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL

Catalog number BNC471970-500

Price for BNC471970-500

Size / count 1x 500 µL

About this product

Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471970-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AITD3; hTG; TDH3; Tg; Tgn
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TG
Gene ID: 7038
NCBI Gene ID: 654591
UniProt: P01266
Swiss Prot: P01266
Host: Rabbit
Species Reactivity: Human
Reactivity: Thyroglobulin
Immunogen: Recombinant full-length human Thyroglobulin protein
Target Antigen: Thyroglobulin
Clonality: Recombinant Monoclonal
Clone: TGB/1970R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: Thyroid
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 660 kDa (Dimeric Form)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL?

The catalog number for Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL is BNC471970-500.

What sizes are available for Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL in stock?

Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e10246b/msds/bnc471970-500.pdf.

What is Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF647 conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.