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Product details

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL

Catalog number BNC472167-500

Price for BNC472167-500

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Size / count 1x 500 µL

About this product

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472167-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
EMD; Emerin; Emery Dreifuss muscular dystrophy (EDMD) ; STA
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EMD
Gene ID
2010
NCBI Gene ID
522823
UniProt
P50402
Swiss Prot
P50402
Host
Mouse
Species Reactivity
Human
Reactivity
Emerin
Immunogen
Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)
Target Antigen
Emerin
Clonality
Monoclonal
Clone
EMD/2167
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Organelle markers
Positive Control
K-562, HeLa or Jurkat cells. Kidney or Skin
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
37 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL?

The catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL is BNC472167-500.

What sizes are available for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL in stock?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e10099f/msds/bnc472167-500.pdf.

What is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF647 conjugate, 0.1mg/mL used for?

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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