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Product details

CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL

Catalog number BNC472395-500

Price for BNC472395-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R à ̄¢ chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex.CD25 antibodies detect three epitope regions, A, B and C. This MAb This antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472395-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IL2RA
Gene ID
3559
NCBI Gene ID
231367
UniProt
P01589
Swiss Prot
P01589
Host
Mouse
Species Reactivity
Human
Reactivity
CD25|IL2RA
Immunogen
Recombinantfragment of human IL2RA protein (around aa 42-183) (exact sequence is proprietary)
Target Antigen
CD25 | IL2RA
Clonality
Monoclonal
Clone
IL2RA/2395
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Immunology
Positive Control
PHA-stimulated human lymphocytes. Human lymph nodeor tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
55 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL?

The catalog number for CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL is BNC472395-500.

What sizes are available for CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL?

CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL in stock?

CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL?

CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e103a0e/msds/bnc472395-500.pdf.

What is CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF647 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cel

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

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