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Product details

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL

Catalog number BNC471813-500

Price for BNC471813-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471813-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BDMF; DMSFH; DMSMFH; Epididymis luminal protein 249; HEL249; LGMBF; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAP; MTAPase; S-methyl-5''-thioadenosine phosphorylase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MTAP
Gene ID
4507
NCBI Gene ID
193268
UniProt
Q13126
Swiss Prot
Q13126
Host
Mouse
Species Reactivity
Human
Reactivity
MTAP
Immunogen
Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary)
Target Antigen
MTAP
Clonality
Monoclonal
Clone
MTAP/1813
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
DNA repair
Positive Control
HepG2, A431, HeLa, HAP1 or MCF-7 cells. Kidney.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
31 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL?

The catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL is BNC471813-500.

What sizes are available for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL in stock?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a6061270361e105dbf/msds/bnc471813-500.pdf.

What is MTAP (Tumor Suppressor Marker) (MTAP/1813), CF647 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding M

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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