BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL — image 1 of 3

Product details

BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL

Catalog number BNC472423-500

Price for BNC472423-500

Size / count 1x 500 µL

About this product

BOB-1 is a transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2, boosting the promoter activity of those complexes. It is essential for the response of B-cells to antigens, required for the formation of germinal centers, and regilates IL-6 expression. BOB-1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB-1. Conversely, only some cases of classical Hodgkin lymphoma show BOB-1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB-1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472423-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BOB-1; B-cell-specific coactivator OBF-1; OCT-binding factor 1; POU domain class 2-associating factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: POU2AF1
Gene ID: 5450
NCBI Gene ID: 654525
UniProt: Q16633
Swiss Prot: Q16633
Host: Mouse
Species Reactivity: Human
Reactivity: BOB.1
Immunogen: Recombinant fragment (around aa 148-255) of human BOB1 (POU2AF1) protein (exact sequence is proprietary)
Target Antigen: BOB.1
Clonality: Monoclonal
Clone: BOB1/2423
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Immunology
Positive Control: Ramos cells. Spleen or Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL?

The catalog number for BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL is BNC472423-500.

What sizes are available for BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL in stock?

BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL?

The safety data sheet for BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e1031a0/msds/bnc472423-500.pdf.

What is BOB.1 (B-Cell Marker) (BOB1/2423), CF647 conjugate, 0.1mg/mL used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.