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Product details
Catalog number BNC472089-500
Price for BNC472089-500
Size / count 1x 500 µL
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of spinal motor neurons, Down syndrome and Alzheimer s disease. In familial ALS, several mutations in SOD-1 predominate, resulting in the loss of zinc binding, the loss of scavenging activity of SOD-1, and correlate with an increase in neurotoxicity and motor neuron death.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is BNC472089-500.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100586/msds/bnc472089-500.pdf.
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.
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