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Product details

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL

Catalog number BNC472309-100

Price for BNC472309-100

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Size / count 1x 100 µL

About this product

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472309-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-2
Gene ID
4821
NCBI Gene ID
516922
UniProt
O95096
Swiss Prot
O95096
Host
Mouse
Species Reactivity
Human
Reactivity
NKX2.2
Immunogen
Human recombinant NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
Target Antigen
NKX2.2
Clonality
Recombinant Monoclonal
Clone
RNX2/1523
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
Pancreas or Ewing's sarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-50 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL?

The catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL is BNC472309-100.

What sizes are available for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL in stock?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL?

The safety data sheet for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1016c8/msds/bnc472309-100.pdf.

What is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), CF647 conjugate, 0.1mg/mL used for?

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be diff

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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