CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL — image 1 of 2

Product details

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472290-100

Price for BNC472290-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP) -activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472290-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7) ; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CFTR
Gene ID: 1080
NCBI Gene ID: 489786, 621460, 661104
UniProt: P13569
Swiss Prot: P13569
Host: Rabbit
Species Reactivity: Human, Mouse
Reactivity: CFTR
Immunogen: Recombinant full-length human CFTR protein
Target Antigen: CFTR
Clonality: Recombinant Monoclonal
Clone: CFTR/2290R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Ion channels
Positive Control: MOLT-4 cells. Pancreas, Kidney or Placenta.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 165-170 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

The catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is BNC472290-100.

What sizes are available for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL in stock?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b2061270361e10a024/msds/bnc472290-100.pdf.

What is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF647 conjugate, 0.1mg/mL used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.