Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL

Catalog number BNC471859-100

Price for BNC471859-100

Size / count 1x 100 µL

About this product

Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471859-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Coagulation Factor VIII; Factor VIII Related Antigen; F8VWF; von Willebrand Antigen 2; von Willebrand Disease (vWD)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: VWF
Gene ID: 7450
NCBI Gene ID: 440848
UniProt: P04275
Swiss Prot: P04275
Host: Rabbit
Species Reactivity: Human
Reactivity: Factor VIII Related-Ag|von Willebrand Factor
Immunogen: Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)
Target Antigen: Factor VIII Related-Ag | von Willebrand Factor
Clonality: Recombinant Monoclonal
Clone: VWF/1859R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Hematology
Positive Control: HUVEC cells. Tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 250 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL?

The catalog number for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL is BNC471859-100.

What sizes are available for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL in stock?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e1077f1/msds/bnc471859-100.pdf.

What is Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), CF647 conjugate, 0.1mg/mL used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.