Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL — image 1 of 3

Product details

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL

Catalog number BNC472089-100

Price for BNC472089-100

Size / count 1x 100 µL

About this product

Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of spinal motor neurons, Down syndrome and Alzheimer s disease. In familial ALS, several mutations in SOD-1 predominate, resulting in the loss of zinc binding, the loss of scavenging activity of SOD-1, and correlate with an increase in neurotoxicity and motor neuron death.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472089-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Amyotrophic lateral sclerosis 1 (ALS1) ; Cu/Zn SOD; Cu/Zn Superoxide Dismutase; Epididymis Secretory Protein Li 44; Indophenoloxidase A (IPOA) ; Superoxide Dismutase [Cu-Zn]; Superoxide Dismutase 1 (SOD1)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SOD1
Gene ID: 6647
NCBI Gene ID: 443914
UniProt: P00441
Swiss Prot: P00441
Host: Mouse
Species Reactivity: Human
Reactivity: Superoxide Dismutase 1
Immunogen: Recombinant full-length human SOD1 protein
Target Antigen: Superoxide Dismutase 1
Clonality: Monoclonal
Clone: SOD1/2089
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Free radicals, Metabolism
Positive Control: HeLa or Jurkat Cells. Breast or Ovarian carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 23 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL?

The catalog number for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is BNC472089-100.

What sizes are available for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL?

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL in stock?

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL?

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b6061270361e10b851/msds/bnc472089-100.pdf.

What is Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF647 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.