Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL

Catalog number BNC471832-100

Price for BNC471832-100

Size / count 1x 100 µL

About this product

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous α andβ chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin α I and spectrinβ I are present in erythrocytes, whereas spectrin α II (also designated fodrin α ) and spectrinβ II (also designated fodrinβ ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471832-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Alpha I spectrin; Elliptocytosis 2 (EL2) ; Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SPTA1
Gene ID: 6708
NCBI Gene ID: 119825
UniProt: P02549
Swiss Prot: P02549
Host: Mouse
Species Reactivity: Human
Reactivity: Spectrin Alpha 1
Immunogen: Recombinant human SPTA fragment (around aa356-475) (exact sequence is proprietary)
Target Antigen: Spectrin Alpha 1
Clonality: Monoclonal
Clone: SPTA1/1832
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cytoskeleton
Positive Control: K562; HeLa; Jurkat cells. Placenta or Tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 240 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL?

The catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL is BNC471832-100.

What sizes are available for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL in stock?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101c5b/msds/bnc471832-100.pdf.

What is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF647 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.